LOUIS BOOTH HUMHRIES was born on January 14, 1859. He was one of seven children of Charles S. Humphries and the former Caroline Fetters, and grandson of Richard Fetters, one of Camden's leading citizens. Charles S. Humphreys started out as a sign paper but soon gained a reputation as an artist. Two of his works hang in the National Art Gallery in Washington, D.C.

The first of the five Humphreys children was born in 1846. Probably from the time of his marriage and definitely from 1867 to 1878, the Humphreys family lived at 41 North Third Street, Camden. Louis Humphreys was the fourth of the five children, coming after Charles F., who was an officer in the United States Navy and who died at the age of 36;  Eveline, who died in infancy; and George W. Humphreys who became an insurance broker in Burlington, New Jersey. The fifth child, Ella F. Humphreys, married Dr. Harry H. Pemberton, of Long Branch, New Jersey.

Louis B. Humphreys stayed in Camden and in his time was one of the most successful and important insurance and real estate brokers in the city, with offices for many years at 230-232 Market Street. The business was carried on by his son, Louis B. Humphreys Jr. and was still a going concern into the 1960s.

Louis Booth Humphreys Sr. passed away in Camden on December 28, 1934.